Letter: faecal volatile organic metabolites, promising biomarkers in inflammatory bowel disease and Letter: faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease. Authors' reply.
نویسندگان
چکیده
منابع مشابه
Faecal gas analysis by electronic nose as novel, non-invasive method for assessment of active and quiescent paediatric inflammatory bowel disease: Proof of principle study.
BACKGROUND AND AIMS Inflammatory bowel disease (IBD) and its two phenotypes ulcerative colitis (UC) and Crohn's disease (CD) are essentially assessed by endoscopy, both in initial diagnostic work-up and during follow-up. This carries a high burden, especially on paediatric patients. Faecal volatile organic compounds (VOCs) are considered potential non-invasive biomarkers for intestinal diseases...
متن کاملFaecal volatile organic compounds analysis using field asymmetric ion mobility spectrometry: non-invasive diagnostics in paediatric inflammatory bowel disease.
BACKGROUND AND OBJECTIVES Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), remains challenging to diagnose. Diagnostic work-up carries a high burden, especially in paediatric patients, due to invasive endoscopic procedures. IBD is associated with alterations in intestinal microbiota composition. Faecal volatile organic compounds (VOCs) reflect gut mi...
متن کاملRole of faecal gas analysis for the diagnosis of IBD.
The diagnosis of IBD (inflammatory bowel disease) is based on the clinical evaluation of symptoms and signs leading to a series of investigations. The investigations used are often unpleasant for patients; they are invasive, costly and potentially dangerous. Patients often report that the odour of flatus, or the gas emitted from faeces, is abnormal during a flare of their IBD. Our group has cha...
متن کاملFaecal calprotectin -- a useful tool in the management of inflammatory bowel disease.
Inflammatory bowel disease (IBD) should be suspected in any patient presenting with chronic or recurrent abdominal pain and diarrhoea. Current guidelines suggest performing invasive endoscopy with histological sampling for further diagnosis. Measuring calprotectin, a neutrophilic protein, in faeces has been proposed as a surrogate marker of intestinal inflammation. Calprotectin values have been...
متن کاملComment on “Biomarkers as Potential Treatment Targets in Inflammatory Bowel Disease: A Systematic Review”
We read with interest the article entitled “Biomarkers as Potential Treatment Targets in Inflammatory Bowel Disease: A Systemic Review,” which brings forward evidence that serum and faecal biomarkers do not possess adequate operational characteristics to make them stand-alone treatment targets in inflammatory bowel disease (IBD) but should be considered as important adjunctive measures to clini...
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عنوان ژورنال:
- Alimentary pharmacology & therapeutics
دوره 43 11 شماره
صفحات -
تاریخ انتشار 2016